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Of the two main incretin hormones released with food ingestion, the actions of glucagon-like peptide-1 (GLP-1) have been exploited for therapeutic benefit

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Mechanisms of GLP-1 receptor agonist-induced weight loss: a review of central and peripheral pathways in appetite and energy regulation

It stimulates insulin secretion from the pancreatic beta cells in a glucose-dependent manner, meaning it only triggers insulin release when blood glucose levels are elevated